Journal article

Trends in Management of Oligometastatic Hormone-Sensitive Prostate Cancer

G Kothari, P Ost, P Cheung, P Blanchard, AC Tree, NJ van As, SS Lo, D Moghanaki, A Loblaw, S Siva

Current Oncology Reports | SPRINGER | Published : 2019

Abstract

Purpose of Review: Systemic therapy for patients with hormone-sensitive oligometastatic prostate cancer is non-curative and associated with toxicities. Meanwhile, this population presents unique clinical opportunities to improve outcomes, including the demonstrated benefits of radiotherapy to the primary tumor or oligometastatic sites. Recent Findings: Recently published randomized studies have demonstrated benefits with the addition of radiotherapy to the primary disease or metastatic lesions in patients with synchronous or metachronous disease. The introduction of novel PET imaging has improved the sensitivity and specificity for detecting metastatic disease and provides an opportunity to ..

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University of Melbourne Researchers

Grants

Funding Acknowledgements

Alison C. Tree and Nicholas J. van As "This paper represents independent research supported by the National Institute for Health Research (NIHR) Biomedical Research Centre at the Royal Marsden NHS Foundation Trust and the Institute of Cancer Research. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health."