Journal article

Is Environmental Enrichment Ready for Clinical Application in Human Post-stroke Rehabilitation?

Matthew W McDonald, Kathryn S Hayward, Ingrid CM Rosbergen, Matthew S Jeffers, Dale Corbett

FRONTIERS IN BEHAVIORAL NEUROSCIENCE | FRONTIERS MEDIA SA | Published : 2018

Abstract

Environmental enrichment (EE) has been widely used as a means to enhance brain plasticity mechanisms (e.g., increased dendritic branching, synaptogenesis, etc.) and improve behavioral function in both normal and brain-damaged animals. In spite of the demonstrated efficacy of EE for enhancing brain plasticity, it has largely remained a laboratory phenomenon with little translation to the clinical setting. Impediments to the implementation of enrichment as an intervention for human stroke rehabilitation and a lack of clinical translation can be attributed to a number of factors not limited to: (i) concerns that EE is actually the "normal state" for animals, whereas standard housing is a form o..

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University of Melbourne Researchers