Screening of CRISPR/Cas base editors to target the AMD high-risk Y402H complement factor H variant
Thuan Nguyen Tran Minh, Mohd Khairul Nizam Mohd Khalid, Alice Pebay, Anthony L Cook, Helena H Liang, Raymond CB Wong, Jamie E Craig, Guei-Sheung Liu, Sandy S Hung, Alex W Hewitt
Molecular Vision | MOLECULAR VISION | Published : 2019
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Awarded by Australian National Health and Medical Research Council (NHMRC) Centres of Research Excellence (CRE)
This work was supported by the Ophthalmic Research Institute of Australia and the Macular Disease Foundation of Australia. Financial support was also obtained from an Australian National Health and Medical Research Council (NHMRC) Centres of Research Excellence (CRE) #1023911 and Project Grant (APP1123329). JEC and AWH are supported by NHMRC Fellowships, while AP is supported by an ARC Future Fellowship. The Centre for Eye Research Australia (CERA) receives Operational Infrastructure Support from the Victorian Government. The contents of the published material are solely the responsibility of the Administering Institution, a Participating Institution or individual authors and do not reflect the views of the NHMRC. We gratefully thank Vikrant Singh for helping with the matlab scripts for base calling and indel formation.