Multidisciplinary home-based rehabilitation in inoperable lung cancer: a randomised controlled trial
Lara Edbrooke, Sanchia Aranda, Catherine L Granger, Christine F McDonald, Mei Krishnasamy, Linda Mileshkin, Ross A Clark, Ian Gordon, Louis Irving, Linda Denehy
THORAX | BMJ PUBLISHING GROUP | Published : 2019
BACKGROUND: Lung cancer is associated with poor health-related quality of life (HRQoL) and high symptom burden. This trial aimed to assess the efficacy of home-based rehabilitation versus usual care in inoperable lung cancer. METHODS: A parallel-group, assessor-blinded, allocation-concealed, randomised controlled trial. Eligible participants were allocated (1:1) to usual care (UC) plus 8 weeks of aerobic and resistance exercise with behaviour change strategies and symptom support (intervention group (IG)) or UC alone. Assessments occurred at baseline, 9 weeks and 6 months. The primary outcome, change in between-group 6 min walk distance (6MWD), was analysed using intention-to-treat (ITT). Su..View full abstract
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Awarded by National Health and Medical Research project grant
This trial was funded through a National Health and Medical Research project grant (APP1060484). LE is the recipient of a Victorian Government Olivia Newton John Cancer Wellness and Research Centre Supportive Care PhD scholarship, through the Victorian Cancer Agency.