Can pre-hospital administration reduce time to initial antibiotic therapy in septic patients?

D Cudini; K Smith; S Bernard; M Stephenson; E Andrew; P Cameron; M Lum; A Udy; V Bennett; J Board; P McCracken; S McGloughlin; V Nanjayya; A Teo; R Bellomo; S Bolch; G Eastwood; F Kerr; L Peak; H Young; J Edington; J Fletcher; J Smith; A Cross; D Flemming; M Grummisch; A Purdue; T Coles; H Connor; J Dennett; A Van Berkel; G Braitberg; B O'Bree; K Shepherd; S Vij; S Allsop; D Haji; K Haji; J Vuat; A Bone; T Elderkin; N Orford; M Ragg; J Dowling; P Galt; T Lamac; D Lightfoot; C Walker; C MacIsaac; K Gorman; A Jordan; L Moore; E Farone; J Holmes; J Santamaria; C Winter; S Bates; J Butler; C French; A Tippett

Journal article

Can pre-hospital administration reduce time to initial antibiotic therapy in septic patients?

D Cudini, K Smith, S Bernard, M Stephenson, E Andrew, P Cameron, M Lum, A Udy, V Bennett, J Board, P McCracken, S McGloughlin, V Nanjayya, A Teo, R Bellomo, S Bolch, G Eastwood, F Kerr, L Peak, H Young Show all

EMA Emergency Medicine Australasia | WILEY | Published : 2019

DOI: 10.1111/1742-6723.13282

Download PDF

Abstract

Objective: To quantify the potential time saved with pre-hospital antibiotic therapy in sepsis. Methods: Study data for adult patients transported by Ambulance Victoria (AV), and enrolled into the Australasian Resuscitation In Sepsis Evaluation (ARISE), were linked with pre-hospital electronic records. Results: An AV record was identified for 240 of 341 ARISE patients. The pre-hospital case notes referred to potential infection in 165 patients. The median time to first antibiotic administration from loading the patient into the ambulance was 107 (74–160) min. Conclusions: ARISE patients in Victoria were frequently identified pre-hospital. An opportunity exists to study the feasibility of pre..

View full abstract