Osteoarthritis- a systematic review of long-term safety implications for osteoarthritis of the knee
Jonathon Charlesworth, Jane Fitzpatrick, Nirmala Kanthi Panagodage Perera, John Orchard
BMC MUSCULOSKELETAL DISORDERS | BMC | Published : 2019
There is no cure for knee osteoarthritis (KOA) and typically patients live approximately 30-years with the disease. Most common medical treatments result in short-term palliation of symptoms with little consideration of long-term risk. This systematic review aims to appraise the current evidence for the long-term (≥12 months) safety of common treatments for knee osteoarthritis (KOA).