Journal article

Long-term mortality and cardiovascular burden for adult survivors of coarctation of the aorta

Melissa GY Lee, Sonya V Babu-Narayan, Aleksander Kempny, Anselm Uebing, Claudia Montanaro, Darryl F Shore, Yves d'Udekem, Michael A Gatzoulis

Heart | BMJ PUBLISHING GROUP | Published : 2019

Abstract

OBJECTIVE: To examine the contemporary long-term outcome after coarctation repair. METHODS: This is a retrospective cohort study of 834 patients aged ≥16 years who underwent coarctation repair under single-centre follow-up. Repair was performed at a median age of 3 years (lower-upper quartile: 1 month to 15 years) by surgery in 83% (690/834) and angioplasty/stenting in 17% (144/834). Survival was compared with an age- and gender matched normal population. Other outcomes included arch reintervention, aortic valve intervention, ascending aortic intervention, and residual/re-coarctation and resting hypertension at latest follow-up. RESULTS: After a median follow-up of 27 years (lower-upper quar..

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Grants

Awarded by National Health and Medical Research Council (NHMRC) Medical Research Postgraduate Scholarship


Awarded by Noel and Imelda Foster Research Award


Awarded by Collaboration and Exchange Award


Awarded by British Heart Foundation


Awarded by NHMRC


Funding Acknowledgements

MGYL is supported by a National Health and Medical Research Council (NHMRC) Medical Research Postgraduate Scholarship (1134274), a National Heart Foundation Health Professional Scholarship supported by The Noel and Imelda Foster Research Award (100681) and Collaboration and Exchange Award (101591), and an Australian Government Research Training Program Scholarship. SVB-N is supported by the British Heart Foundation (FS/11/38/28864). Yves d'Udekem is an NHMRC Clinician Practitioner Fellow (1082186).