Journal article

Systemic treatment of advanced hepatocellular cancer: new hope on the horizon.

Rachael Chang Lee, Niall Tebbutt

Expert Rev Anticancer Ther | Published : 2019

Abstract

INTRODUCTION: Hepatocellular carcinoma (HCC) is among the leading causes of cancer-related mortality in the world. The majority of the patients present at an advanced or incurable stage where neither locoregional treatment nor combination treatment of locoregional treatment and systemic therapies is feasible. For decades sorafenib was the only treatment option available for advanced HCC. However, with the advent of new and more effective therapies recently, the overall prognosis of advanced HCC has improved significantly. Areas covered: This review summarises the current systemic treatment options available and future prospects in the management of advanced HCC where patients are not suitabl..

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University of Melbourne Researchers