Journal article
Nutraceuticals and nutritional supplements for the treatment of bipolar disorder: Protocol for a systematic review
MM Ashton, M Berk, CH Ng, M Hopwood, B Kavanagh, LJ Williams, J Sarris, OM Dean
BMJ Open | Published : 2019
Open access
Abstract
Introduction First line pharmacological treatments for bipolar disorder (BD) can leave shortfalls in recovery leading to patients seeking alternative and adjunctive treatments such as nutraceuticals. This protocol for a systematic review and proposed meta-analysis aims to answer the research question: in patients with BD, how does use of nutraceutical treatments compare with placebo in reducing depressive and mania symptoms? Methods and analysis Clinical trials will be identified through database searches using PubMed via PubMed, EMBASE via embase.com, Cochrane Central Register of Controlled Clinical Trials (CENTRAL) via cochranelibrary.com and CINAHL Complete via EBSCO. Search terms for BD ..
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Awarded by Deakin University
Funding Acknowledgements
The authors would like to acknowledge the NHMRC Project Grant Scheme (APP1121510) for supporting this review. MMA would further like to acknowledge the support of Australian Rotary Health/Ian Parker Bipolar Research Fund PhD scholarship and the ASBDD/Lundbeck PhD neuroscience scholarship. MB is supported by a NHMRC Senior Principal Research Fellowship (APP1059660). BK is supported by Deakin University, the Australian Government Research Training Program Scholarship and Australian Rotary Health. LJW is supported by a NHMRC Career Development Fellowship (APP1064272). JS is supported by an NHMRC Clinical Research Fellowship (APP1125000). OMD is supported by a NHMRC R.D. Wright Biomedical Research Fellowship (APP1145634). No funding bodies had any role in developing the protocol.