Journal article

The Framingham and UK Prospective Diabetes Study (UKPDS) risk equations do not reliably estimate the probability of cardiovascular events in a large ethnically diverse sample of patients with diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron-MR Controlled Evaluation (ADVANCE) Study.

AP Kengne, A Patel, S Colagiuri, S Heller, P Hamet, M Marre, CY Pan, S Zoungas, DE Grobbee, B Neal, J Chalmers, M Woodward, undefined ADVANCE Collaborative Group

Diabetologia | Published : 2010

Abstract

AIMS/HYPOTHESIS: Available multivariable equations for cardiovascular risk assessment in people with diabetes have been derived either from the general population or from populations with diabetes. Their utility and comparative performance in a contemporary group of patients with type 2 diabetes are not well established. The aim of this study was to evaluate the performance of the Framingham and UK Prospective Diabetes Study (UKPDS) risk equations in participants who took part in the Action in Diabetes and Vascular disease: Preterax and Diamicron-MR Controlled Evaluation (ADVANCE) trial. METHODS: The 4-year risks of cardiovascular disease (CVD) and its constituents were estimated using two p..

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University of Melbourne Researchers