Journal article

Geometry of a TLR2-Agonist-Based Adjuvant Can Affect the Resulting Antigen-Specific Immune Response

Acep R Wijayadikusumah, Weiguang Zeng, Hayley A McQuilten, Chinn Yi Wong, David C Jackson, Brendon Y Chua

Molecular Pharmaceutics | AMER CHEMICAL SOC | Published : 2019

DOI: 10.1021/acs.molpharmaceut.9b00026

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Keywords

Protein Conformation
Adjuvants, Pharmaceutic
Lipopeptide
Lipopeptides
Toll-Like Receptor-2
Antibody
Hek293 Cells
Dendritic Cell
Mice, Inbred Balb C
Science & Technology
Toll-Like Receptor 2
Mice, Transgenic
Peptides
Life Sciences & Biomedicine
Ovalbumin
Static Electricity
Particle Size
Mice, Inbred C57bl
Mice
Research & Experimental Medicine
Humans
Cd8(+) T-Cell
Immunogens
Susceptibility
Interferon-Gamma
Medicine, Research & Experimental
Vaccine
Cd8-Positive T-Lymphocytes
Adjuvants, Immunologic
Animals
Maturation
Cells, Cultured
Cd8+ T Cells
Tlr2
Pharmacology & Pharmacy
Antibodies
Signal Transduction
Dendritic Cells
Antigen Presentation
Cd8(+) T Cells