Journal article

Evaluation of Risk Factors for Severe Pneumonia in Children: The Pneumonia Etiology Research for Child Health Study

Chizoba B Wonodi, Maria Deloria-Knoll, Daniel R Feikin, Andrea N DeLuca, Amanda J Driscoll, Jennifer C Moisi, Hope L Johnson, David R Murdoch, Katherine L O'Brien, Orin S Levine, J Anthony G Scott

CLINICAL INFECTIOUS DISEASES | OXFORD UNIV PRESS INC | Published : 2012

Abstract

As a case-control study of etiology, the Pneumonia Etiology Research for Child Health (PERCH) project also provides an opportunity to assess the risk factors for severe pneumonia in hospitalized children at 7 sites. We identified relevant risk factors by literature review and iterative expert consultation. Decisions for inclusion in PERCH were based on comparability to published data, analytic plans, data collection costs and logistic feasibility, including interviewer time and subject fatigue. We aimed to standardize questions at all sites, but significant variation in the economic, cultural, and geographic characteristics of sites made it difficult to obtain this objective. Despite these c..

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University of Melbourne Researchers

Grants

Awarded by The Bill & Melinda Gates Foundation


Awarded by The Wellcome Trust of Great Britain


Awarded by MRC


Funding Acknowledgements

This work was supported by grant 48968 from The Bill & Melinda Gates Foundation to the International Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health. J. A. G. S. is supported by a clinical fellowship from The Wellcome Trust of Great Britain (number 081835). This article was published as part of a supplement entitled "Pneumonia Etiology Research for Child Health,'' sponsored by a grant from The Bill & Melinda Gates Foundation to the PERCH Project of Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.