Journal article

Laboratory Methods for Determining Pneumonia Etiology in Children

Niranjan Bhat, Katherine L O'Brien, Ruth A Karron, Amanda J Driscoll, David R Murdoch

CLINICAL INFECTIOUS DISEASES | OXFORD UNIV PRESS INC | Published : 2012

Abstract

Laboratory diagnostics are a core component of any pneumonia etiology study. Recent advances in diagnostic technology have introduced newer methods that have greatly improved the ability to identify respiratory pathogens. However, determining the microbial etiology of pneumonia remains a challenge, especially in children. This is largely because of the inconsistent use of assays between studies, difficulties in specimen collection, and problems in interpreting the presence of pathogens as being causally related to the pneumonia event. The laboratory testing strategy for the Pneumonia Etiology Research for Child Health (PERCH) study aims to incorporate a broad range of diagnostic testing that..

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Grants

Awarded by The Bill & Melinda Gates Foundation


Funding Acknowledgements

This work was supported by grant 48968 from The Bill & Melinda Gates Foundation to the International Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health.This article was published as part of a supplement entitled "Pneumonia Etiology Research for Child Health,'' sponsored by a grant from The Bill & Melinda Gates Foundation to the PERCH Project of Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.