Journal article

Abdominal aortic calcification, bone mineral density and fractures: a systematic review and meta-analysis protocol

Alexander J Rodriguez, Kevin Leow, Pawel Szulc, David Scott, Peter Ebeling, Marc Sim, Germaine Wong, Wai H Lim, John T Schousboe, Douglas P Kiel, Richard L Prince, Joshua R Lewis

BMJ OPEN | BMJ PUBLISHING GROUP | Published : 2019

Abstract

INTRODUCTION: Abdominal aortic calcification (AAC) is associated with low bone mass and increased fracture risk. Two previous meta-analyses have investigated the association between AAC and fracture. However, these meta-analyses only identified articles until December 2016, undertook limited searches and did not explore potential sources of between-study heterogeneity. We aim to undertake a sensitive and comprehensive assessment of the relationship between AAC, bone mineral density (BMD) as well as prevalent and incident fractures. METHODS: We will search MEDLINE, EMBASE, Web of Science core collection and Google Scholar (top 200 articles sorted by relevance) from their inception to 1 June 2..

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University of Melbourne Researchers

Grants

Awarded by National Health and Medical Research Council of Australia (NHMRC) Career Development Fellowship


Funding Acknowledgements

The salaries of JRL and DS are supported by a National Health and Medical Research Council of Australia (NHMRC) Career Development Fellowship (ID: 1107474 and 1123014, respectively).