Journal article

Evidence for a new paradigm of gonorrhoea transmission: cross-sectional analysis of Neisseria gonorrhoeae infections by anatomical site in both partners in 60 male couples

Vincent Jasper Cornelisse, Deborah Williamson, Lei Zhang, Marcus Y Chen, Catriona Bradshaw, Jane S Hocking, Jennifer Hoy, Benjamin P Howden, Eric PF Chow, Christopher K Fairley



OBJECTIVE: Gonorrhoea transmission between men is currently thought to occur primarily to and from the urethra. Transmission without urethral involvement, from throat-to-throat and throat-to-anus, is considered to be uncommon. Using gonorrhoea results from male couples, we aimed to investigate the transmission dynamics of gonorrhoea. If current medical consensus is correct, then most throat and anal infections should be explained by the partner's urethral infection. METHODS: This is a cross-sectional analysis of gonorrhoea diagnosed by nucleic acid amplification tests in both partners in male couples who attended Melbourne Sexual Health Centre together between March 2015 and June 2017. Isola..

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Awarded by Australian National Health and Medical Research Council (NHMRC)

Awarded by NHMRC

Funding Acknowledgements

This work was supported by the Australian National Health and Medical Research Council (NHMRC) programme grant (no: 568971). EPFC is supported by the Early Career Fellowships from the NHMRC (no: 1091226). VJC is supported by a Research Training Scheme Scholarship from the Australian Government's Department of Education and Training. DW is supported by an Early Career Fellowships from the NHMRC (APP1123854). BPH is supported by a Practitioner Fellowship (GNT1105905). VJC had full access to all data in this study and takes final responsibility for the decision to submit for publication.