Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes

Saireudee Chaturantabut; Arkadi Shwartz; Kimberley J Evason; Andrew G Cox; Kyle Labella; Arnout G Schepers; Song Yang; Mariana Acuna; Yariv Houvras; Liliana Mancio-Silva; Shannon Romano; Daniel A Gorelick; David E Cohen; Leonard Zon; Sangeeta N Bhatia; Trista E North; Wolfram Goessling

Journal article

Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes

Saireudee Chaturantabut, Arkadi Shwartz, Kimberley J Evason, Andrew G Cox, Kyle Labella, Arnout G Schepers, Song Yang, Mariana Acuna, Yariv Houvras, Liliana Mancio-Silva, Shannon Romano, Daniel A Gorelick, David E Cohen, Leonard Zon, Sangeeta N Bhatia, Trista E North, Wolfram Goessling

Gastroenterology | W B SAUNDERS CO-ELSEVIER INC | Published : 2019

DOI: 10.1053/j.gastro.2019.01.010

University of Melbourne Researchers

Andrew Cox Author Biochemistry and Molecular Biology

Grants

Awarded by National Institutes of Health

Funding Acknowledgements

This study is supported by National Institutes of Health 5K08CA172288 (to Kimberley J. Evason), R24OD017870 (to Leonard I. Zon and Wolfram Goessling), R37DK048873, R01DK056626 and R01 DK103046 (to David E. Cohen) and R01DK090311 and R01DK105198 (to Wolfram Goessling), and the Claudia Adams Barr Program in Cancer Research (to Wolfram Goessling). Wolfram Goessling is a Pew Scholar in the Biomedical Sciences.