Knowledge Gaps and Emerging Research Areas in Intrauterine Growth Restriction-Associated Brain Injury
Bobbi Fleiss, Flora Wong, Fiona Brownfoot, Isabelle K Shearer, Olivier Baud, David W Walker, Pierre Gressens, Mary Tolcos
FRONTIERS IN ENDOCRINOLOGY | FRONTIERS MEDIA SA | Published : 2019
Intrauterine growth restriction (IUGR) is a complex global healthcare issue. Concerted research and clinical efforts have improved our knowledge of the neurodevelopmental sequelae of IUGR which has raised the profile of this complex problem. Nevertheless, there is still a lack of therapies to prevent the substantial rates of fetal demise or the constellation of permanent neurological deficits that arise from IUGR. The purpose of this article is to highlight the clinical and translational gaps in our knowledge that hamper our collective efforts to improve the neurological sequelae of IUGR. Also, we draw attention to cutting-edge tools and techniques that can provide novel insights into this d..View full abstract
The funders played no role in the decision to publish or the content of the publication. (Cerebral Palsy Alliance; National Health and Medical Council of Australia; Australian Research Council; ANR-French Research Agency).