Journal article

Biotechnological potential of engineering pathogen effector proteins for use in plant disease management

Angela P Van de Wouw, Alexander Idnurm



A key component in the management of many diseases of crops is the use of plant disease resistance genes. However, the discovery and then sequence identification of these plant genes is challenging, whereas the characterization of the molecules that they recognize, the effector/avirulence products in pathogens, is often considerably more straight forward. Effectors are small proteins secreted by pathogens that can play major roles in modulating a plant's defense against attack. Effectors can be used to guide breeding of resistance genes, to trigger defense responses, and are part of integrated disease management strategies for crop protection. This review covers the role of effector-driven b..

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Awarded by Australian Grains Research and Development Corporation

Funding Acknowledgements

We thank Barbara Howlett for comments on the manuscript. Al was a recipient of the Robert Lipp Plant Science Memorial Research Fellowship from the University of Melbourne. This work was also supported in part by the Australian Grains Research and Development Corporation (projects UM00050 and UM00051).