Journal article

Genetic risk, body mass index, and weight control behaviors: Unlocking the triad

Jason M Nagata, David B Braudt, Benjamin W Domingue, Kirsten Bibbins-Domingo, Andrea K Garber, Scott Griffiths, Stuart B Murray



BACKGROUND: The relationship between genetic risk for body mass index (BMI) and weight control behaviors remains unknown. The objectives of this study were to determine the association between genetic risk for BMI and weight control behaviors in young adults, and to examine actual measured BMI as a potential mediator variable. METHOD: We analyzed data from three data collection waves of the National Longitudinal Study of Adolescent to Adult Health. The BMI polygenic score (PGS) was based on published genome-wide association studies for BMI. BMI was collected at 11-18 years and 18-26 years. Weight control behaviors included self-reported: (a) weight loss behaviors (dieting, vomiting, fasting/..

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Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awarded by National Health and Medical Research Council

Awarded by National Institute of Mental Health

Funding Acknowledgements

Eunice Kennedy Shriver National Institute of Child Health and Human Development, Grant/ Award Numbers: 5R01HD082166-02, K12HD00085033; National Health and Medical Research Council, Grant/Award Number: 1121538; National Institute of Mental Health, Grant/Award Number: K23 MH115184