Journal article

Role of personality disorder in randomised controlled trials of pharmacological interventions for adults with mood disorders: A protocol for a systematic review and meta-analysis

BE Kavanagh, SL Brennan-Olsen, A Turner, OM Dean, M Berk, MM Ashton, H Koivumaa-Honkanen, LJ Williams

BMJ Open | BMJ PUBLISHING GROUP | Published : 2019

Abstract

Introduction Remission rates for mood disorders, including depressive and bipolar disorders, remain relatively low despite available treatments, and many patients fail to respond adequately to these interventions. Evidence suggests that personality disorder may play a role in poor outcomes. Although personality disorders are common in patients with mood disorders, it remains unknown whether personality disorder affects treatment outcomes in mood disorders. We aim to review currently available evidence regarding the role of personality disorder on pharmacological interventions in randomised controlled trials for adults with mood disorders. Methods and analysis A systematic search of Cochrane ..

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University of Melbourne Researchers

Grants

Awarded by Australian Rotary Health


Funding Acknowledgements

BEK is supported by an Australian Government Research Training Program Scholarship and an Australian Rotary Health Ian Scott PhD Scholarship. SLB-O is supported by an NHMRC Career Development Fellowship (APP1107510). OMD is supported by a NHMRC R.D. Wright Biomedical Research Fellowship (APP1145634). MB is supported by an NHMRC Senior Principal Research Fellowship (APP1059660 and APP1156072). MMA is supported by Australian Rotary Health/Ian Parker Bipolar Research Fund PhD Scholarship and the ASBDD/Lundbeck PhD Neuroscience Scholarship. HK-H is supported by Kuopio University Hospital. LJW is supported by an NHMRC Career Development Fellowship (APP1064272).