Journal article

Extended-spectrum beta-lactamase in the rectal flora of patients undergoing transrectal prostate biopsy: a study of the prevalence in a major metropolitan hospital

James Sewell, Ken Chow, Antonio De Sousa, Nikhil Sapre, Briony Norris, Benjamin Namdarian, Vincent Sinickas, James G Huang, Paul Anderson

BJU INTERNATIONAL | WILEY | Published : 2019

Abstract

OBJECTIVES: To determine the prevalence of extended-spectrum β-lactamase (ESBL) in patients undergoing transrectal prostate biopsy, to assess the incidence of postoperative sepsis, to correlate the development of sepsis with the presence of preoperative ESBL on rectal swabs, and to assess the adequacy of prophylactic antibiotic guidelines in the context of local ESBL prevalence. METHODS: Patients undergoing transrectal ultrasonography (TRUS)-guided biopsy at the Royal Melbourne Hospital between January 2012 and July 2016 had rectal swabs taken immediately prior to TRUS with specific cultures to identify the presence of ESBL. Patients were given a prophylactic antibiotic, 500 mg oral ciproflo..

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University of Melbourne Researchers