Journal article

Influence of occlusion site and baseline ischemic core on outcome in patients with ischemic stroke

Huiqiao Tian, Mark W Parsons, Christopher R Levi, Longting Lin, Richard I Aviv, Neil J Spratt, Kenneth S Butcher, Min Lou, Timothy J Kleinig, Andrew Bivard

Neurology | LIPPINCOTT WILLIAMS & WILKINS | Published : 2019

Abstract

OBJECTIVE: We assessed patient clinical outcomes based on occlusion location, focusing on distal occlusions to understand if occlusion location was an independent predictor of outcome, and tested the relationship between occlusion location and baseline ischemic core, a known predictor of modified Rankin Scale (mRS) score at 90 days. METHODS: We analyzed a prospectively collected cohort of thrombolysis-eligible ischemic stroke patients from the International Stroke Perfusion Imaging Registry who underwent multimodal CT pretreatment. For the primary analysis, logistic regression was used to predict the effect of occlusion location and ischemic core on the likelihood of excellent (mRS 0-1) and ..

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Grants

Awarded by National Health and Medical Research Council Australia Partnership Project Grant


Awarded by National Health and Medical Research Council Practitioner Fellowship


Awarded by National Health and Medical Research Council/National Heart Foundation


Funding Acknowledgements

Supported by a National Health and Medical Research Council Australia Partnership Project Grant (APP1013719). Christopher R. Levi is funded by a National Health and Medical Research Council Practitioner Fellowship (APP 1043913). Neil J. Spratt is funded by a National Health and Medical Research Council/National Heart Foundation co-funded Career Development/Future Leader Fellowship (APPS1110629/100827). Longting Lin is supported by The Science and Industry Endowment Fund (SIEF) STEM + Business Fellowship.