Journal article

What Evidence Do We Have for Pharmaceutical Galactagogues in the Treatment of Lactation Insufficiency?A Narrative Review

Luke E Grzeskowiak, Mary E Wlodek, Donna T Geddes

NUTRIENTS | MDPI | Published : 2019

Abstract

Inadequate breast milk supply is a frequently reported reason for early discontinuation of breastfeeding and represents a critical opportunity for intervening to improve breastfeeding outcomes. For women who continue to experience insufficient milk supply despite the utilisation of non-pharmacological lactation support strategies, pharmacological intervention with medications used to augment lactation, commonly referred to as galactagogues, is common. Galactagogues exert their pharmacological effects through altering the complex hormonal milieu regulating lactation, particularly prolactin and oxytocin. This narrative review provides an appraisal of the existing evidence regarding the efficac..

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Grants

Awarded by Australia National Health and Medical Research Council (NHMRC) Early Career Fellowship


Funding Acknowledgements

L.E.G. acknowledges the salary support provided by an Australia National Health and Medical Research Council (NHMRC) Early Career Fellowship (GNT 1070421), Robinson Research Institute Career Development Fellowship and Lloyd Cox Research Fellowship. D.T.G. acknowledges the salary support provided by an unrestricted research grant from Medela AG (Switzerland).