Journal article

Low recurrence of lung adenoid cystic carcinoma with radiotherapy and resection

Varun J Sharma, Ankit Gupta, Nima Yaftian, David Ball, Robin Brown, Stephen Barnett, Phillip Antippa

ANZ JOURNAL OF SURGERY | WILEY | Published : 2019

Abstract

BACKGROUND: Adenoid cystic carcinoma is a rare cause of thoracic malignancy, and the prognosis may depend on the extent of surgical resection and adjuvant radiotherapy. Complete resection has low rates of local recurrence but is complicated by the involvement of central airways. Adjuvant radiotherapy is frequently recommended but unproven. METHODS: We describe the technicalities of radical resection and adjuvant radiotherapy using the primary endpoint of local recurrence and secondary endpoints of locoregional (mediastinal) recurrence and distant metastasis. Resections were classed as microscopically and macroscopically clear (R0) or only macroscopically clear (R1). RESULTS: Twelve patients ..

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