Journal article

Economic evaluation in the context of rare diseases: is it possible?

Everton Nunes da Silva, Tanara Rosangela Vieira Sousa

CADERNOS DE SAUDE PUBLICA | CADERNOS SAUDE PUBLICA | Published : 2015

Abstract

This study analyzes the available evidence on the adequacy of economic evaluation for decision-making on the incorporation or exclusion of technologies for rare diseases. The authors conducted a structured literature review in MEDLINE via PubMed, CRD, LILACS, SciELO, and Google Scholar (gray literature). Economic evaluation studies had their origins in Welfare Economics, in which individuals maximize their utilities based on allocative efficiency. There is no widely accepted criterion in the literature to weigh the expected utilities, in the sense of assigning more weight to individuals with greater health needs. Thus, economic evaluation studies do not usually weigh utilities asymmetrically..

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Funding Acknowledgements

This article is an adapted version of the technical report submitted by co-author T.R.V.S. to the National Commission on the Incorporation of Technologies by the Brazilian Unified National Health System (Conitec/MS), for which she received funding from the institution. However, Conitec/MS did not exert any influence whatsoever on the elaboration of the article. In addition, the authors take full responsibility for the opinions expressed here.