Journal article

The effect of high-protein, low-carbohydrate diets in the treatment of type 2 diabetes: a 12 month randomised controlled trial

RN Larsen, NJ Mann, E Maclean, JE Shaw

DIABETOLOGIA | SPRINGER | Published : 2011


AIMS/HYPOTHESIS: Short-term dietary studies suggest that high-protein diets can enhance weight loss and improve glycaemic control in people with type 2 diabetes. However, the long-term effects of such diets are unknown. The aim of this study was to determine whether high-protein diets are superior to high-carbohydrate diets for improving glycaemic control in individuals with type 2 diabetes. METHODS: Overweight/obese individuals (BMI 27-40 kg/m(2)) with type 2 diabetes (HbA(1c) 6.5-10%) were recruited for a 12 month, parallel design, dietary intervention trial conducted at a diabetes specialist clinic (Melbourne, VIC, Australia). Of the 108 initially randomised, 99 received advice to follow ..

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Awarded by NHMRC

Funding Acknowledgements

This study was funded by a nutritional research grant from Meat and Livestock Australia (MLA). J. E. Shaw is supported by NHMRC Fellowship 586623.Duality of interest J. E. Shaw has received grants, honoraria and speakers' fees from: GlaxoSmithKline, Lilly Pharmaceuticals, Bristol Myers Squibb, Astra Zeneca, Pfizer, Merck Sharp and Dolme, and Novo Nordisk. N. Mann has received two nutrition grants from MLA in the last 5 years. The protocol and execution of the study was the responsibility of the investigators. MLA had no role in the study design, data collection, data analysis, data interpretation or the decision to submit this paper for publication.