Journal article
Association of Antidementia Therapies With Time to Skilled Nursing Facility Admission and Cardiovascular Events Among Elderly Adults With Alzheimer Disease
Alvaro San-Juan-Rodriguez, Yuting Zhang, Meiqi He, Inmaculada Hernandez
JAMA Network Open | JAMA Network | Published : 2019
Abstract
Importance To date, no study has compared time to skilled nursing facility (SNF) admission and cardiovascular events across medications available to treat Alzheimer disease. Objective To compare time to SNF admission and cardiovascular events between acetylcholinesterase inhibitor (AChEI) monotherapy, memantine hydrochloride monotherapy, and combination therapy with an AChEI and memantine in treating elderly adults with Alzheimer disease. Design, Setting, and Participants This retrospective cohort study uses January 1, 2006, to December 31, 2014, claims data from a 5% random sample of Medicare beneficiaries who had received a new diagnosis of Alzheimer disease between January 1, 2007, a..
View full abstractGrants
Awarded by Alzheimer's Association
Awarded by National Heart, Lung, and Blood Institute
Funding Acknowledgements
This study was funded by grant AARGD-17-500234 from the Alzheimer's Association. Dr Hernandez is funded by grant K01HL142847 from the National Heart, Lung, and Blood Institute.