Journal article

Effect of Macronutrient Composition on Appetite Hormone Responses in Adolescents with Obesity

Kay Nguo, Maxine P Bonham, Helen Truby, Elizabeth Barber, Justin Brown, Catherine E Huggins

NUTRIENTS | MDPI | Published : 2019


Gut appetite hormone responses may be influenced by meal macronutrients and obesity. The primary aim of this study was to examine in adolescents with obesity and of healthy weight the effect of a high-protein and a high-carbohydrate meal on postprandial gut appetite hormones. A postprandial cross-over study with adolescents 11⁻19 years old was undertaken. Participants consumed, in random order, a high 79% carbohydrate (HCHO) and a high 55% protein (HP) meal. Ghrelin, glucagon-like peptide 1 (GLP-1), peptide YY (PYY), and self-reported appetite were assessed for four hours postprandial. Total energy intake from an ad libitum lunch and remaining 24 h was assessed. Eight adolescents with obesit..

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University of Melbourne Researchers