Journal article

Influence of dietary modifications on the blood pressure response to antihypertensive medication

Catherine E Huggins, Claire Margerison, Anthony Worsley, Caryl A Nowson



Identifying dietary modifications that potentiate the blood pressure (BP)-lowering effects of antihypertensive medications and that are practical for free-living people may assist in achieving BP reduction goals. We assessed whether two dietary patterns were effective in lowering BP in persons on antihypertensive therapy and in those not on therapy. Ninety-four participants (38/56 females/males), aged 55·6 (SD 9·9) years, consumed two 4-week dietary regimens in random order (Dietary Approaches to Stop Hypertension (DASH)-type diet and low- Na high-K (LNAHK) diet) with a control diet before each phase. Seated home BP was measured daily for the last 2 weeks in each phase. Participants were gro..

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University of Melbourne Researchers


Funding Acknowledgements

The authors have no conflicts of interest to declare. The present study was funded by the Dairy Research and Development Corporation, and they had no involvement in the study design; in the collection, analysis and interpretation of data; in the writing of the manuscript; or in the decision to submit the manuscript for publication. The technical support of M. K. Jorna, S. J. Torres and S. J. Godfrey is acknowledged. C. E. H. conducted data analyses and writing of the manuscript. C. M. conducted the dietary counselling and participated in the data collection. A. W. and C. A. N. conceived the study, participated in the study design and coordinated the data collection. All the authors contributed to re-drafting, and read and approved the final manuscript.