Journal article

Tuning Elasticity of Open-Cell Solid Foams and Bone Scaffolds via Randomized Vertex Connectivity

Susan Nachtrab, Sebastian C Kapfer, Dominik Rietzel, Dietmar Drummer, Mahyar Madadi, Christoph H Arns, Andrew M Kraynik, Gerd E Schroeder-Turk, Klaus Mecke

ADVANCED ENGINEERING MATERIALS | WILEY-V C H VERLAG GMBH | Published : 2012

Abstract

Tuning mechanical properties of and fluid flow through open-cell solid structures is a challenge for material science, in particular for the design of porous structures used as artificial bone scaffolds in tissue engineering. We present a method to tune the effective elastic properties of custom-designed open-cell solid foams and bone scaffold geometries by almost an order of magnitude while approximately preserving the pore space geometry and hence fluid transport properties. This strong response is achieved by a change of topology and node coordination of a network-like geometry underlying the scaffold design. Each node of a four-coordinated network is disconnected with probability p into ..

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University of Melbourne Researchers

Grants

Funding Acknowledgements

We are grateful to Carl Fruth (FIT GmbH, Parsberg) and Alexander Oster (NetFabb GmbH, Parsberg) for post-processing the sample data and producing multiple samples, free of charge. Many thanks to Jurgen Karsten for assistance with the mechanical testing. SN, GEST and KM acknowledge funding by the Deutsche Forschungsgemeinschaft (DFG) through the Cluster of Excellence "Engineering of Advanced Materials'' in Erlangen. DD and DR acknowledge funding by the LGA Nordbayern (Leitprojekte Medizintechnik, BayMED). SN, GEST, CHA and MM acknowledge travel support by the German academic exchange service (DAAD) and the Australian Group of Eight universities through a joint program. Supporting Information is available from the Wiley Online Library or from the author.