Identifying Possible Outcome Domains from Existing Outcome Measures to Inform an OMERACT Core Domain Set for Safety in Rheumatology Trials
Louise Klokker, Dorthe B Berthelsen, Thasia Woodworth, Kathleen M Andersen, Daniel E Furst, Dan Devoe, Paula R Williamson, Maria E Suarez-Almazor, Vibeke Strand, Amye L Leong, Niti Goel, Maarten Boers, Peter M Brooks, Lyn March, Victor S Sloan, Peter Tugwell, Lee S Simon, Robin Christensen
JOURNAL OF RHEUMATOLOGY | J RHEUMATOL PUBL CO | Published : 2019
OBJECTIVE: The Outcome Measures in Rheumatology (OMERACT) Safety Working Group objective was to identify harm domains from existing outcome measurements in rheumatology. METHODS: Systematically searching the MEDLINE database on January 24, 2017, we identified full-text articles that could be used for harm outcomes in rheumatology. Domains/items from the identified instruments were described and the content synthesized to provide a preliminary framework for harm outcomes. RESULTS: From 435 possible references, 24 were read in full text and 9 were included: 7 measurement instruments were identified. Investigation of domains/items revealed considerable heterogeneity in the grouping and approach..View full abstract
Awarded by Oak Foundation
The Parker Institute, Bispebjerg and Frederiksberg Hospital is supported by a core grant from the Oak Foundation (OCAY-13-309).