Journal article

Volumetric analysis of tumor extent in nasopharyngeal carcinoma and correlation with treatment outcome

DTT Chua, JST Sham, DLW Kwong, KS Tai, PM Wu, M Lo, A Yung, D Choy, L Leong

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | PERGAMON-ELSEVIER SCIENCE LTD | Published : 1997

Abstract

PURPOSE: To investigate the variability of tumor volume in nasopharyngeal carcinoma using quantitative measurements of tumor bulk derived from computed tomography, and to study the prognostic value of tumor volume in comparison with other variables. METHODS AND MATERIALS: Two hundred ninety patients with newly diagnosed nasopharyngeal carcinoma were included in the study. The primary tumor volume (PTV) and nodal tumor volume (NTV) were obtained by outlining the tumor contour followed by summation of areas in sequential pretreatment computed tomography axial scans. Total tumor volume (TTV) was obtained by adding the PTV and NTV. All patients had radiotherapy as the primary treatment, 67 patie..

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University of Melbourne Researchers