Journal article

Evolution of Plant-Made Pharmaceuticals

David R Thomas, Claire A Penney, Amrita Majumder, Amanda M Walmsley

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | MDPI AG | Published : 2011

Abstract

The science and policy of pharmaceuticals produced and/or delivered by plants has evolved over the past twenty-one years from a backyard remedy to regulated, purified products. After seemingly frozen at Phase I human clinical trials with six orally delivered plant-made vaccines not progressing past this stage over seven years, plant-made pharmaceuticals have made a breakthrough with several purified plant-based products advancing to Phase II trials and beyond. Though fraught with the usual difficulties of pharmaceutical development, pharmaceuticals made by plants have achieved pertinent milestones albeit slowly compared to other pharmaceutical production systems and are now at the cusp of re..

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University of Melbourne Researchers