Conference Proceedings
RELATIONSHIP BETWEEN SCHIZOTYPY AND SUBCORTICAL BRAIN VOLUMES IN 1084 INDIVIDUALS VIA THE ENIGMA CONSORTIUM
Mathilde Antoniades, Alexander Fornito, Melissa Green, Christos Pantelis, Pamela DeRosse, Martin Debbane, Igor Nenadic, Christian Gaser, Bianca Besteher, Matthias Kirschner, Stefan Kaiser, Iris Sommer, Kelly Diederen, Jan-Bernard Marsman, Veena Kumari, Raymond Chan, Yann Quide, Wulf Rossler, Haeme Park, Irina Lebedeva Show all
SCHIZOPHRENIA BULLETIN | OXFORD UNIV PRESS | Published : 2019
Abstract
Neuroanatomical studies have provided some evidence for a neurobiological continuity between psychotic symptoms in patients with schizophrenia and subclinical psychotic-like experiences as identified via self-report questionnaires (or schizotypy) in otherwise healthy individuals. Despite a number of structural brain imaging studies published in subjects with schizotypy, these have often been limited by relatively small sample sizes. This study represents the first meta-analysis of structural MRI scans in schizotypy assessed with standardized methods at 17 centres worldwide. The total sample included in the case-control meta-analysis involved 496 subjects with high schizotypy and 588 comparis..
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