ASSOCIATIONS BETWEEN BRAIN MORPHOLOGY AND COGNITION IN INDIVIDUALS WITH SCHIZOPHRENIA AND BIPOLAR DISORDER: A REVIEW

Abstract

Although nosologically distinct, there is overlap in the disease presentation of individuals with schizophrenia (Sz) and bipolar disorder (BD). Both disorders are characterized by abnormalities in cognitive performance, and in brain volume, cortical thickness and surface area. It is possible that these abnormalities are related, however the nature of the brain structure-cognition relationship in these disorders is inconclusive. This review aims to elucidate the association between measures of brain morphology and cognitive impairment in Sz and BD. Science Direct, PubMed, NCBI, and Web of Science databases were searched for papers investigating cognition and brain morphology in Sz and BD. Stu..