Journal article

Perspective: Advancing Understanding of Population Nutrient-Health Relations via Metabolomics and Precision Phenotypes

Stephanie Andraos, Melissa Wake, Richard Saffery, David Burgner, Martin Kussmann, Justin O'Sullivan

Advances in Nutrition | OXFORD UNIV PRESS | Published : 2019

Abstract

Diet and lifestyle are vital to population health, but their true contribution is difficult to quantify using traditional methods. Nutrient-health relations are typically based on epidemiological associations that are assessed at the population level, traditionally using self-reported dietary and lifestyle data. Unfortunately, such measures are inherently inaccurate. New technologies such as metabolomics can measure nutritional and micronutrient profiles in body fluids, providing objective evaluation of nutritional status. A critical step toward accurate health prediction models would be the building of integrated repositories of nutritional measures combining subjective methods of reporting..

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Grants

Awarded by Ministry of Business, Innovation & Employment catalyst grant


Awarded by Australian National Health and Medical Research Council (NHMRC)


Awarded by NHMRC Principal Research Fellowship


Funding Acknowledgements

Supported by Ministry of Business, Innovation & Employment catalyst grant UOAX1611 (The New Zealand-Australia LifeCourse Collaboration on Genes, Environment, Nutrition and Obesity), the New Zealand International Doctoral Research Scholarship 2017 and the Liggins Institute doctoral research scholarship (to SA), Australian National Health and Medical Research Council (NHMRC) Senior Research Fellowship APP1064629 (to DB), and NHMRC Principal Research Fellowship 1160906 (to MW).