Contributors to frailty in critical illness: Multi-dimensional analysis of the Clinical Frailty Scale

Abstract

PURPOSE: Frailty in critical illness is common and associated with poor outcomes, however little is known about contributing factors. We compared the Clinical Frailty Scale (CFS) with a multi-dimensional validated tool, the Edmonton Frail Scale (EFS), and investigated which health domains are affected by frailty in ICU. MATERIALS AND METHODS: This prospective cohort study enrolled patients aged ≥50 years admitted between February-June 2017, comparing the CFS and EFS using Spearman correlation and Kappa coefficients, assessing frailty status across health domains, and examining outcomes including mortality. RESULTS: One hundred and sixty patients were enrolled, 33.8% were frail. Frail patient..