Journal article
Association of Childhood Oral Infections With Cardiovascular Risk Factors and Subclinical Atherosclerosis in Adulthood
PJ Pussinen, S Paju, J Koponen, JSA Viikari, L Taittonen, T Laitinen, DP Burgner, M Kähönen, N Hutri-Kähönen, OT Raitakari, M Juonala
JAMA Network Open | AMER MEDICAL ASSOC | Published : 2019
Abstract
Importance: Severe forms of common chronic oral infections or inflammations are associated with increased cardiovascular risk in adults. To date, the role of childhood oral infections in cardiovascular risk is not known because no long-term studies have been conducted. Objective: To investigate whether signs of oral infections in childhood are associated with cardiovascular risk factors and subclinical atherosclerosis in adulthood. Design, Setting, and Participants: The cohort study (n = 755) was derived from the Cardiovascular Risk in Young Finns Study, an ongoing prospective cohort study in Finland initiated in 1980. Participants underwent clinical oral examinations during childhood, when ..
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Awarded by Horizon 2020 Framework Programme
Funding Acknowledgements
The current study, the Cardiovascular Risk in Young Finns Study, and the researchers were supported by the Academy of Finland grants 1266053, 1296541, 286284, 134309 (Eye), 126925, 121584, 124282, 129378 (Salve), 117787 (Gendi), and 41071 (Skidi); the Social Insurance Institution of Finland; Competitive State Research Financing of the Expert Responsibility area of Kuopio, Tampere and Turku University Hospitals (grant X51001); Juho Vainio Foundation; Paavo Nurmi Foundation; Finnish Foundation for Cardiovascular Research; Finnish Cultural Foundation; the Sigrid Juselius Foundation; Tampere Tuberculosis Foundation; Emil Aaltonen Foundation; Yrjo Jahnsson Foundation; Signe and Ane Gyllenberg Foundation; the European Endodontic Society; Apollonia the Dental Association of Finland; the Paulo foundation; Diabetes Research Foundation of Finnish Diabetes Association; EU Horizon 2020 (grant 755320 for TAXINOMISIS); European Research Council (grant 742927 for MULTIEPIGEN project); and Tampere University Hospital Supporting Foundation.