Journal article

Choroid plexus volume after stroke

Natalia Egorova, Elie Gottlieb, Mohamed Salah Khlif, Neil J Spratt, Amy Brodtmann

International Journal of Stroke | SAGE PUBLICATIONS LTD | Published : 2019

Abstract

BACKGROUND: Cerebrospinal fluid circulation is crucial for the functioning of the brain. Aging and brain pathologies such as Alzheimer's disease have been associated with a change in the morphology of the ventricles and the choroid plexus. Despite the evidence from animal models that the cerebrospinal fluid system plays an important role in neuroinflammation and the restoration of the brain after ischemic brain injury, little is known about changes to the choroid plexus after stroke in humans. AIMS: Our goal was to characterize structural choroid plexus changes poststroke. METHODS: We used an automatic segmentation tool to estimate the volumes of choroid plexus and lateral ventricles in stro..

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