Journal article

Associations of pigmentary and naevus phenotype with melanoma risk in two populations with comparable ancestry but contrasting levels of ambient sun exposure

AE Cust, M Drummond, DT Bishop, L Azizi, H Schmid, MA Jenkins, JL Hopper, BK Armstrong, JF Aitken, RF Kefford, GG Giles, F Demenais, AM Goldstein, JH Barrett, PA Kanetsky, DE Elder, GJ Mann, JA Newton-Bishop

Journal of the European Academy of Dermatology and Venereology | WILEY | Published : 2019


BACKGROUND: People at high risk of developing melanoma are usually identified by pigmentary and naevus phenotypes. OBJECTIVE: We examined whether associations of these phenotypes with melanoma risk differed by ambient sun exposure or participant characteristics in two population-based, case-control studies with comparable ancestry but different ambient sun exposure. METHODS: Data were analysed from 616 cases and 496 controls from the Australian Melanoma Family Study and 2012 cases and 504 controls from the Leeds (UK) case-control study. Questionnaire, interview and dermatological skin examination data were collected using the same measurement protocols. Relative risks were estimated as odds ..

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Awarded by Cancer Research UK

Awarded by National Health and Medical Research Council of Australia (NHMRC)

Awarded by NCI NIH HHS

Awarded by the Cancer Council New South Wales

Awarded by the US National Institutes of Health

Awarded by the Cancer Council Victoria and the Cancer Council Queensland

Awarded by Cancer Institute NSW