Journal article

Conservative versus conventional oxygen therapy for cardiac surgical patients: A before-and-after study

Glenn M Eastwood, Matthew J Chan, Leah Peck, Helen Young, Johan Martensson, Neil J Glassford, Hidetoshi Kagaya, Satoshi Suzuki, Sean Galvin, George Matalanis, Rinaldo Bellomo

Anaesthesia and Intensive Care | SAGE PUBLICATIONS LTD | Published : 2019


Avoiding hypoxaemia is considered crucial in cardiac surgery patients admitted to the intensive care unit (ICU). However, avoiding hyperoxaemia may also be important. A conservative approach to oxygen therapy may reduce exposure to hyperoxaemia without increasing the risk of hypoxaemia. Using a before-and-after design, we evaluated the introduction of conservative oxygen therapy (target SpO2 88%-92% using the lowest FiO2) for cardiac surgical patients admitted to the ICU. We studied 9041 arterial blood gas (ABG) datasets: 4298 ABGs from 245 'conventional' and 4743 ABGs from 298 'conservative' oxygen therapy patients. During mechanical ventilation (MV) and while in the ICU, compared to the co..

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Funding Acknowledgements

The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the Anaesthesia Intensive Care Trust Fund, Austin Hospital, Melbourne, Victoria.