Journal article
Surgical and Survival Outcomes Following Pelvic Exenteration for Locally Advanced Primary Rectal Cancer Results From an International Collaboration
ME Kelly, R Glynn, AGJ Aalbers, W Alberda, A Antoniou, KK Austin, GL Beets, J Beynon, SJ Bosman, M Brunner, MW Buchler, JWA Burger, N Campain, HK Christensen, M Codd, M Coscia, A Colquhoun, I Daniels, RJ Davies, JHW de Wilt Show all
ANNALS OF SURGERY | LIPPINCOTT WILLIAMS & WILKINS | Published : 2019
Abstract
OBJECTIVE: The aim of the study was to analyze data from an international collaboration, and ascertain prognostic indicators that inform clinical decision-making and practices regarding the role of pelvic exenteration for locally advanced primary rectal cancer (LARC). BACKGROUND: With improved national screening programs fewer patients present with LARC. Despite this, select cohorts of patients require pelvic exenteration. To date, the majority of outcome data are from single-center series. METHODS: Anonymized data from 14 countries on patients who had pelvic exenteration for LARC between 2004 and 2014 were accumulated. The primary endpoint was overall survival. The impact of resection margi..
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