Journal article

The future burden of kidney and bladder cancers preventable by behavior modification in Australia: A pooled cohort study

Maarit A Laaksonen, Robert J MacInnis, Karen Canfell, Graham G Giles, Peter Hull, Jonathan E Shaw, Robert G Cumming, Tiffany K Gill, Emily Banks, Paul Mitchell, Julie E Byles, Dianna J Magliano, Vasant Hirani, David Connah, Claire M Vajdic



Substantial changes in the prevalence of the principal kidney and bladder cancer risk factors, smoking (both cancers) and body fatness (kidney cancer), have occurred but the contemporary cancer burden attributable to these factors has not been evaluated. We quantified the kidney and bladder cancer burden attributable to individual and joint exposures and assessed whether these burdens differ between population subgroups. We linked pooled data from seven Australian cohorts (N = 367,058) to national cancer and death registries and estimated the strength of the associations between exposures and cancer using adjusted proportional hazards models. We estimated exposure prevalence from representat..

View full abstract


Awarded by Cancer Institute New South Wales

Awarded by National Health and Medical Research Council of Australia

Funding Acknowledgements

Grant sponsor: Cancer Institute New South Wales; Grant number: ID13/ECF/1-07; Grant sponsor: National Health and Medical Research Council of Australia; Grant numbers: ID1053642, ID1060991, ID1079438, ID1082989, ID1118161, ID1136128, ID301916, ID396414, ID209057; Grant sponsor: Ageing and Alzheimer's Institute; Grant sponsor: Cancer Council Victoria; Grant sponsor: VicHealth