CAN WE RECOMMEND COGNITIVE REMEDIATION THERAPY FOR SCHIZOPHRENIA?

Abstract

Cognitive impairment is a core feature of schizophrenia that contributes to functional disability. Pharmacological treatments have little to no effect on cognitive deficits. Cognitive remediation therapy (CRT) has emerged as a moderately effective treatment in ameliorating cognitive deficits. However, a number of limitations have been identified in the literature which have impacted the strength of recommendations for clinical translation. These include, but are not limited to: reported variability in response to CRT with some patients not realising any benefit; it is unknown to what extent there is functional generalisation; it is unknown what the role of intrinsic motivation on treatment e..