Journal article

Prodromal symptoms and remission following first episode psychosis.

Laoise Renwick, John Lyne, Brian O Donoghue, Liz Owens, Roisin Doyle, Michele Hill, Emma McCarthy, Mark Pilling, Eadbhard O'Callaghan, Mary Clarke

Schizophrenia Research | Elsevier BV | Published : 2015

Abstract

INTRODUCTION: Describing the trajectory of prodromal symptoms has obvious appeal in supporting advances towards sub-clinical intervention. Identifying clinical phenomena associated with unfavourable illness outcomes could have greater significance in explaining some heterogeneity within and between psychotic disorders and advancing understanding of pre-psychotic typologies. Few studies have assessed the continuity, if any, between prodromal phases and illness outcome one year after treatment. METHODS: We assessed 375 people with first-episode psychosis (FEP) and 215 (57.4%) were seen approximately one year later. We performed factor analysis on prodromal symptom items obtained by interview w..

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