Journal article
Candidaemia and a risk predictive model for overall mortality: A prospective multicentre study
C Keighley, SCA Chen, D Marriott, A Pope, B Chapman, K Kennedy, N Bak, N Underwood, HL Wilson, K McDonald, J Darvall, C Halliday, S Kidd, Q Nguyen, K Hajkowicz, TC Sorrell, S Van Hal, MA Slavin
BMC Infectious Diseases | BMC | Published : 2019
Open access
Abstract
Background: Candidaemia is associated with high mortality. Variables associated with mortality have been published previously, but not developed into a risk predictive model for mortality. We sought to describe the current epidemiology of candidaemia in Australia, analyse predictors of 30-day all-cause mortality, and develop and validate a mortality risk predictive model. Methods: Adults with candidaemia were studied prospectively over 12 months at eight institutions. Clinical and laboratory variables at time of blood culture-positivity were subject to multivariate analysis for association with 30-day all-cause mortality. A predictive score for mortality was examined by area under receiver o..
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Funding Acknowledgements
This work was supported in part by an educational grant from MSD Australia. MSD Australia had no role in the design of the study, data collection, analysis, interpretation of data or writing of the manuscript.