Phase I trial of the single-chain urokinase intrapleural LTI-01 in complicated parapneumonic effusions or empyema
Lutz Beckert, Ben Brockway, Graham Simpson, Anne Marie Southcott, YC Gary Lee, Najib Rahman, Richard W Light, Steven Shoemaker, John Gillies, Andrey A Komissarov, Galina Florova, Timothy Ochran, William Bradley, Harrison Ndetan, Karan P Singh, Krishna Sarva, Steven Idell
JCI Insight | AMER SOC CLINICAL INVESTIGATION INC | Published : 2019
Awarded by NIH SMARTT
Awarded by NIH
Awarded by NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
NIH SMARTT HHSN268201100014C (SI) provided funding of the manufacturing of the drug substance, toxicology studies, and regulatory support; NIH UO-1 HL121841-01A1 (SI) provided initial funding in preparation for the clinical trial.