Phase I trial of the single-chain urokinase intrapleural LTI-01 in complicated parapneumonic effusions or empyema
Lutz Beckert, Ben Brockway, Graham Simpson, Anne Marie Southcott, YC Gary Lee, Najib Rahman, Richard W Light, Steven Shoemaker, John Gillies, Andrey A Komissarov, Galina Florova, Timothy Ochran, William Bradley, Harrison Ndetan, Karan P Singh, Krishna Sarva, Steven Idell
JCI Insight | AMER SOC CLINICAL INVESTIGATION INC | Published : 2019
Awarded by NIH SMARTT
Awarded by NIH
NIH SMARTT HHSN268201100014C (SI) provided funding of the manufacturing of the drug substance, toxicology studies, and regulatory support; NIH UO-1 HL121841-01A1 (SI) provided initial funding in preparation for the clinical trial.