Conference Proceedings

Treatment sequencing and outcomes in synchronous metastatic rectal cancer.

Madeleine Cornelia Strach, Margaret Lee, Anna Lomax, Michael Ng, Mario Guerrieri, Thiru Prasanna, Hui-li Wong, Belinda Lee, Joseph James McKendrick, Lionel Lim, Suzanne Kosmider, Jeanne Tie, Desmond Yip, Louise M Nott, Julie Johns, Michael Harold, Peter Gibbs, Rachel Wong

JOURNAL OF CLINICAL ONCOLOGY | AMER SOC CLINICAL ONCOLOGY | Published : 2017

Abstract

750 Background: Optimal sequencing of therapies in synchronous metastatic rectal cancer (SMRC) remains unknown. Aim: To compare sequencing of treatment modality and outcomes in SMRC. Methods: Retrospective audit of patients with SMRC registered on the multi-centre Treatment of Recurrent and Advanced Colorectal Cancer database between 1/1/2009 and 30/6/2015. Patients were grouped according to initial treatment mode: chemotherapy (C), chemoradiation (CRT), surgery (S) and best supportive care (BSC). Results: 247 patients were identified: median age was 62yrs, ECOG 0-1 87%, male 64%, 1-2 metastatic sites 86% (liver 56%) and treatment intent was curative in 14%. Median follow-up was 19m. Primar..

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