Journal article

Limited Sustained Local Transmission of HIV-1 CRF01_AE in New South Wales, Australia

Francesca Di Giallonardo, Angie N Pinto, Phillip Keen, Ansari Shaik, Alex Carrera, Hanan Salem, Barbara Telfer, Craig Cooper, Karen Price, Christine Selvey, Joanne Holden, Nadine Bachmann, Frederick J Lee, Dominic E Dwyer, Sebastian Duchene, Edward C Holmes, Andrew E Grulich, Anthony D Kelleher, Rebecca Guy, Garrett Prestage Show all

VIRUSES-BASEL | MDPI | Published : 2019


Australia's response to the human immunodeficiency virus type 1 (HIV-1) pandemic led to effective control of HIV transmission and one of the world's lowest HIV incidence rates-0.14%. Although there has been a recent decline in new HIV diagnoses in New South Wales (NSW), the most populous state in Australia, there has been a concomitant increase with non-B subtype infections, particularly for the HIV-1 circulating recombinant form CRF01_AE. This aforementioned CRF01_AE sampled in NSW, were combined with those sampled globally to identify NSW-specific viral clades. The population growth of these clades was assessed in two-year period intervals from 2009 to 2017. Overall, 109 NSW-specific clade..

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Awarded by Swiss National Science Foundation

Awarded by NHMRC

Awarded by Australian Laureate Fellowship

Funding Acknowledgements

This work was supported by the Swiss National Science Foundation (P300PA_174462 to F.D.G.), the Practitioner Fellowship, the NHMRC Postgraduate Scholarship (APP1074467 to A.N.P.), and the Australian Laureate Fellowship (FL170100022 to E.C.H.). This analysis was further supported by funding from NHMRC Partnership (APP1092852) and Practitioner Fellowship (APP117907) Grants, the NSW Ministry of Health, and UNSW Sydney. The Kirby Institute receives funding from the Australian Government Department of Health and is affiliated with the Faculty of Medicine, UNSW Sydney. No pharmaceutical industry grants were received for this study.