Journal article

Impact of Pre-Procedural Blood Pressure on Long-Term Outcomes Following Percutaneous Coronary Intervention

J Warren, S Nanayakkara, N Andrianopoulos, A Brennan, D Dinh, M Yudi, D Clark, AE Ajani, CM Reid, L Selkrig, J Shaw, C Hiew, M Freeman, D Kaye, BA Kingwell, AM Dart, SJ Duffy, E Oqueli, A Walton, A Broughton Show all

Journal of the American College of Cardiology | ELSEVIER SCIENCE INC | Published : 2019

Abstract

Background: High systolic blood pressure (SBP)increases cardiac afterload, whereas low diastolic blood pressure (DBP)may lead to impaired coronary perfusion. Thus, wide pulse pressure (high systolic, low diastolic [HSLD])may contribute to myocardial ischemia and also be a predictor of adverse cardiovascular events. Objectives: The purpose of this study was to determine the relationship between pre-procedural blood pressure and long-term outcome following percutaneous coronary intervention (PCI). Methods: The study included 10,876 consecutive patients between August 2009 and December 2016 from the Melbourne Interventional Group registry undergoing PCI with pre-procedural blood pressure record..

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Grants

Funding Acknowledgements

The Melbourne Interventional Group has received unrestricted educational grant funding from Abbott Vascular, AstraZeneca, Medtronic, Merck Sharp & Dohme, Pfizer, Servier, and The Medicines Company. These companies do not have access to the data, and do not have the right to review manuscripts before publication. Dr Nanayakkara is supported by a Heart Foundation Health Professional Scholarship and a Baker Bright Sparks scholarship. Dr. Yudi is supported by a combined National Health and Medical Research Council and National Heart Foundation Postgraduate Scholarship. Prof. Reid's and Prof. Duffy's work is funded by National Health and Medical Research Council of Australia Grants. Dr. Kingwell has research grant contracts with CSL Ltd. that are unrelated to the current publication. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose. George Bakris, MD, served as Guest Associate Editor for this paper. A full list of the Melbourne Interventional Group Investigators can be found in the Online Appendix.